Two new antineoplastic diterpenes from taxus mairei.
نویسندگان
چکیده
منابع مشابه
New taxane diterpenoids from the roots of Taiwanese Taxus mairei.
Five new taxane diterpenoids, taxumairols G (1), H (2), I (3), J (4), and L (5) were isolated from extracts of the roots of Taiwanese Taxus mairei (LEMEE & LEVL.) S. Y. Hu. Compounds 1-4 belong to the new 11(15-->1)-abeo-taxene system, having a tetrahydrofuran ring along carbons C-2, C-3, C-4 and C-20. Compounds 3 and 4 contain an isopropenyl group at C-1 while compounds 1 and 2 are attached wi...
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Two new clerodane-type diterpenes, tinosporins C (1) and tinosporins D (2) were isolated from the stems of Tinospora sagittata (Oliv.), together with three known ones, columbin (3), tinophylloloside (4), and tinospinoside D (5). The structures of these compounds were determined on the basis of spectroscopic data interpretation, with that of the absolute configuration of compound 1 was assigned ...
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The objective of this study was to isolate endophytic fungi producing paclitaxel from yew for the purpose of paclitaxel manufacture. Surface sterilized bark of Taxus wallichiana var. mairei was used as source material and potato dextrose agar culture medium was used in isolation of endophytic fungi. Fungal cultures were extracted with a mixture of chloroform / methanol (1:1, v/v) and the paclit...
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Paclitaxel is a medicinal ingredient with high anticancer activity and widely used in hospitals and clinics. In this study, we isolate endophytic fungi efficiently producing paclitaxel from yew for the purpose of paclitaxel manufacture.The bark of Taxus wallichiana var. mairei was surface sterilized and then inoculated in potato dextrose agar culture medium to isolate endophytic fungi. The pacl...
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Two new diterpenes namely verbenacine (1) and salvinine (2) have been isolated from the aerial parts of Salvia verbenaca. Their structures have been elucidated on the basis of chemical and spectral data as 3alpha-hydroxy-19-carboxykaur-15-ene and 19-hydroxy-12,14-dioxo labda-15,17-diene.
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1987
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.35.2613